Mischievous class clowns George (Kevin Hart) and Harold (Thomas Middleditch) create a comic book centered on the superhero Captain Underpants. After they hypnotize their mean high school principal Mr. Krupp (Ed Helms), however, Captain Underpants becomes part of their reality.
Diana (Gal Gadot), princess of the Amazons, has been trained to be an unconquerable warrior on her closely guarded Amazon homeland of Paradise Island. When an American plane crashes on the shores of the island and the pilot reveals that there's a massive conflict taking place, Diana decides she has to step in to help.
When Dean's (Demetri Martin) mother dies, he is forced to evaluate his life. He's a New York illustrator and realizes he longs for more, so relocates to Los Angeles and begins to find himself. Still in New York, Dean's father Robert (Kevin Kline) deals with his wife's passing in a much different way.