"I look like the Flash about to get married."
The two major storylines that have revolved around Howard are his relationship with Bernadette, and him becoming an astronaut. In this episode, once again, these two storylines entwine themselves together, but in an unlikely manner.
"Word of caution, I would not do your Stephen Hawking impression in front of him."
Over the years, Sheldon has looked down on both Howard and Penny, for having insufficient education. Howard has always felt like he was getting disrespected, and that his master's degree in engineering was not as worthless as Sheldon had treated it to be.
"And just to clarify... a female wife?"
The inability to speak to women has been a long source of agony for Raj. It took a huge toll on him in the last episode, "The Weekend Vortex," as he expressed his frustration of Sheldon beating him to getting into a relationship before he did.
The Agreement Dissection was split up into four parts, following a storyline that could only happen to Sheldon. The episode started with Sheldon running into Leonard and Priya in the bathroom, which Sheldon reacted later by pulling out the dreaded roommate agreement.
There is a subtle joke that is played out in this episode. The joke not only targeted the characters, but also the viewer. Throughout the episode, there is the assumption that Bernadette was going to break up with Howard. This assumption became the plot, wherein everybody gossiped about.
World of Warcraft is a place on the internet where lots of drama occurs. On the surface, it is just a game, but to Sheldon, it is more than a game. To him, it is his on-line alternate life. In this alternate life, Sheldon has spent a huge amount of time leveling up, and collecting virtual items. It comes as no surprise that Sheldon would react badly when he was hacked.